Adaptive vs. regular deep brain stimulation for Parkinson's
Part of Brain & nervous system clinical trials.
This study compares two ways of using deep brain stimulation (DBS) — an adjustable ‘adaptive’ version that changes with your brain signals, versus the standard continuous setting. It aims to see which works better for people with Parkinson's disease who already have a specific type of DBS device.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Parkinson's disease by a neurologist using standard UK criteria.
- You are 18 years or older.
- You already have a Medtronic Percept PC or RC DBS system implanted in both sides of the brain targeting a deep area called the subthalamic nucleus (STN).
- The electrical contact that best manages your symptoms can work with the adaptive DBS mode in at least one side of the brain.
- There is a reliable beta brain signal (a type of brain wave) in at least one side of the brain.
- You can give informed consent and follow the study procedures.
- You understand the Dutch language.
- You are not pregnant, do not have dementia or mild cognitive impairment, and are not legally incompetent or in another trial for brain treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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