Clin2
NCT04702932Possibly a fitNot yet recruiting

Gene and protein study of blood cells in inflammatory blood diseases

Monoclonal Gammopathy of Undetermined SignificanceMultiple MyelomaWaldenstrom Macroglobulinemia

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study looks at blood cells from people with certain blood conditions who also have fevers with no clear cause. It aims to understand the genetic and functional features of these cells, which may help explain why fever and inflammation happen. You will likely have a blood sample taken for testing, and the results may inform future treatments, though the study itself does not test a new treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must be 18 years or older and able to give your own consent.
  • You must have one of these blood conditions: myelodysplastic syndrome (a bone marrow problem), multiple myeloma (a blood cancer), MGUS (a pre-cancerous blood condition), or Schnitzler's syndrome (a rare inflammatory disease).
  • You must have a fever with no known cause, along with one of these symptoms: rash, joint pain or swelling, inflammation around your heart or lungs, or belly pain.
  • You must be able to speak French and answer questions for the study.
  • Your symptoms must not already be explained by another illness.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02269592Recruiting
Study blood marker changes in early, symptom-free blood cancers

This study follows people with early, “precursor” blood conditions to learn what changes in their blood or bone marrow signal progression. It may help doctors better predict outcomes and understand why some people develop symptom-causing cancer.

Boston, Massachusetts
NCT06539832Recruiting
Gut bacteria and immunity in people with an abnormal blood protein

This study looks at how your gut bacteria (intestinal flora) and immune system relate to a condition called monoclonal gammopathy, where an abnormal protein is found in the blood. The trial will check samples from your blood, plasma, and stool to understand these connections.

Guanzhou, Guangdong
NCT05968417Recruiting
Study of new lab tests using blood or bone marrow samples for myeloma

This trial studies myeloma (and closely related blood disorders) by using extra blood or bone marrow samples for lab research. It aims to help discover new ways to understand or treat myeloma.

Sutton
NCT02726750Recruiting
Study of early plasma cell blood conditions before myeloma

This is an observational study that follows people with early blood findings that can be linked to multiple myeloma, to understand what happens over time. It does not test a new drug for most people; instead, it tracks health, lab results, and imaging to learn who may develop myeloma.

Houston, Texas
NCT05383339Recruiting
Testing blood markers in autoimmune, vasculitis, and autoinflammation

This study looks at blood “biomarkers,” or measurable body signals, in people with autoimmune diseases, vasculitis, or autoinflammatory conditions. The goal is to better understand these illnesses and how they relate to disease activity.

Paris, France
NCT07471074Recruiting
Study of stem cells in Waldenström macroglobulinemia

This study looks at bone marrow stem cells in people with Waldenström macroglobulinemia (WM). It aims to understand how these cells work and may help improve future treatments for WM.

Amiens

Hear when a new Monoclonal Gammopathy of Undetermined Significance trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.