Clin2
NCT04713787Possibly a fitRecruiting

Test higher doses of oxfendazole against single-dose albendazole

Trichuriasis

Treatments studied

Part of Infections clinical trials.

This trial studies which dose of oxfendazole works best and is safest for treating a specific intestinal worm infection in adults. It compares different oxfendazole doses to one standard dose of albendazole, and uses stool and blood testing over about 4–6 weeks.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
249 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You’re age 18 to 65 (and weigh at least 45 kg).
  • Your stool test within the last 14 days confirms you have Trichuris trichiura (a whipworm).
  • You agree to collect about four stool samples and two blood samples over ~4–6 weeks.
  • If you’ve had anti-worm medicine in the last 14 days, you can’t join.
  • If you can become pregnant, you must have a negative pregnancy test and use effective birth control during the study and for about 28 days after.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07661316Not yet recruiting· Phase 3
New deworming drug combinations for whipworm in children

This study tests new combinations of deworming medicines to treat whipworm infection in school-aged children in Honduras. It aims to find a more effective treatment for children with this parasitic infection.

Tegucigalpa
NCT05706116Recruiting· Phase 1
Study gives worm eggs by mouth to healthy adults

This Phase 1 trial tests how safe and tolerated orally taken Trichuris trichiura (a type of intestinal worm) eggs are in healthy adults. It aims to help researchers understand early safety and study setup before any future treatments.

Washington D.C., District of Columbia
NCT03435718Not yet recruiting· Phase 2
Oxfendazole for adults with whipworm infection

This trial tests whether oxfendazole can better treat whipworm (Trichuris trichiura) in adults by checking stool samples before and after treatment. You may be eligible if you’ve recently had whipworm found in stool and can return for multiple follow-up samples.

NCT06367361Not yet recruiting· Phase 2
Comparing oxfendazole with triclabendazole for chronic liver fluke

This study tests whether one or two doses of oxfendazole (a newer drug) works as well as the standard two-dose triclabendazole treatment for chronic fascioliasis (liver fluke infection). It may offer a simpler treatment option.

NCT07258173Not yet recruiting· Phase 2
Comparing two drugs for whipworm infection

This trial tests a new drug, emodepside, against the standard treatment albendazole for whipworm infection. It aims to see which is safer and works better in adolescents and adults.

NCT07074444Recruiting· Phase 4
Treating clonorchiasis with three different drugs

This study compares three medicines (albendazole, tribendimidine, and praziquantel) to see which works best for treating clonorchiasis (a liver fluke infection). If you have been diagnosed with this infection, this trial may help find the most effective treatment for you.

Nanning, Guangxi

Hear when a new Trichuriasis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.