Oxfendazole for mild brain cysticercosis
Part of Brain & nervous system, Infections clinical trials.
This trial tests a new oral drug called oxfendazole to treat a mild form of brain infection caused by the pork tapeworm. The goal is to see if it can safely clear the infection and reduce symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Brain scans (CT or MRI) show one or two small cysts or an enhancing spot (granuloma) that is likely from the pork tapeworm.
- You have not taken albendazole or praziquantel for brain cysticercosis in the past year.
- Your basic blood tests (hemoglobin, white blood cells, liver and kidney function) are normal.
- You are not pregnant, and if you could become pregnant, you agree to use reliable birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a combination of two medicines (praziquantel and albendazole) works better than one medicine (albendazole alone) for treating a parasitic brain infection that causes seizures. Participants will be hospitalized for up to 20 days and followed for one year to see how well the infection clears and if symptoms improve.
This trial studies which dose of oxfendazole works best and is safest for treating a specific intestinal worm infection in adults. It compares different oxfendazole doses to one standard dose of albendazole, and uses stool and blood testing over about 4–6 weeks.
This study tests whether one or two doses of oxfendazole (a newer drug) works as well as the standard two-dose triclabendazole treatment for chronic fascioliasis (liver fluke infection). It may offer a simpler treatment option.
This trial tests whether oxfendazole can better treat whipworm (Trichuris trichiura) in adults by checking stool samples before and after treatment. You may be eligible if you’ve recently had whipworm found in stool and can return for multiple follow-up samples.
This early-phase study tests whether certain anti-fungal “azole” pills can help control recurring high-grade gliomas (a type of aggressive brain tumor) after the tumor comes back. It’s meant for adults whose medical team believes the recurrence is real tumor growth and who may need another surgical procedure.
This study compares three medicines (albendazole, tribendimidine, and praziquantel) to see which works best for treating clonorchiasis (a liver fluke infection). If you have been diagnosed with this infection, this trial may help find the most effective treatment for you.
Hear when a new Brain Cysticercosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.