Comparing oxfendazole with triclabendazole for chronic liver fluke
Treatments studied
Part of Digestive system, Infections clinical trials.
This study tests whether one or two doses of oxfendazole (a newer drug) works as well as the standard two-dose triclabendazole treatment for chronic fascioliasis (liver fluke infection). It may offer a simpler treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- A stool test within the last 14 days has confirmed you have fasciola (liver fluke) eggs.
- You have not been treated for fasciola before.
- If you are a woman, you are not pregnant, nursing, or planning to become pregnant, and you agree to use birth control.
- You do not have serious liver or kidney disease, and you are not taking certain medications that could interact with the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies which dose of oxfendazole works best and is safest for treating a specific intestinal worm infection in adults. It compares different oxfendazole doses to one standard dose of albendazole, and uses stool and blood testing over about 4–6 weeks.
This trial tests whether oxfendazole can better treat whipworm (Trichuris trichiura) in adults by checking stool samples before and after treatment. You may be eligible if you’ve recently had whipworm found in stool and can return for multiple follow-up samples.
This study compares three medicines (albendazole, tribendimidine, and praziquantel) to see which works best for treating clonorchiasis (a liver fluke infection). If you have been diagnosed with this infection, this trial may help find the most effective treatment for you.
This study tests if higher doses of arpraziquantel can safely treat children infected with the liver fluke Opisthorchis viverrini. It aims to find the best dose that clears the infection.
This trial tests a new oral drug called oxfendazole to treat a mild form of brain infection caused by the pork tapeworm. The goal is to see if it can safely clear the infection and reduce symptoms.
This trial tests a new drug, emodepside, against the standard treatment albendazole for whipworm infection. It aims to see which is safer and works better in adolescents and adults.
Hear when a new Fascioliasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.