Medicines to improve sleep after knee replacement
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether taking mirtazapine and quetiapine can improve sleep after a total knee replacement (TKA). It may help if pain and stress after surgery are keeping you awake.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for or have had a total knee replacement (TKA)
- You are not currently using benzodiazepines (anti-anxiety/sleep medicines)
- You are not currently taking anti-depressants
- You are not taking oxycodone (a strong opioid pain medicine)
- You do not have obstructive sleep apnea or severe breathing problems or myasthenia
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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