Study lung pressure treatment for people waiting for transplant
Part of Lungs & breathing clinical trials.
This Phase 2 trial is for adults with pulmonary hypertension who are on the lung transplant waiting list at Duke. It aims to test whether the study treatment can improve lung pressure and related health outcomes, while using things like MRI to monitor changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Be on the lung transplant waiting list at Duke University Medical Center
- Have pulmonary hypertension confirmed by a right-heart catheter test (mPAP > 20 and PVR > 3, with PCWP < 15)
- Have one of these lung-heart diagnoses: PAH, COPD, or IPF, with the study group depending on test results for precapillary PH
- Be able and willing to sign consent and follow all study visits and rules
- Be able to safely do MRI scans (no unsafe metal in body/eyes, able to lie flat, and able to tolerate the scanner)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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