Teriflunomide for HTLV-1 spinal cord stiffness and weakness
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This early-phase trial tests whether teriflunomide can help people with HTLV-1 associated myelopathy (HAM) or tropical spastic paraparesis (TSP). It also checks safety and how well the treatment can be followed over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older
- Have HAM/TSP confirmed by testing showing HTLV-1 (positive screening test and confirmatory blood test)
- Be enrolled in the specific related study group (98-N-0047)
- Be able and willing to take pills by mouth, follow visit schedules, and give informed consent
- Have a negative tuberculosis blood test (or complete treatment if it’s positive)
- Use reliable birth control if you could become pregnant or father a child, during treatment and for 2 years after stopping
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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