Testing an added breathing therapy for ARDS patients on ventilators
Part of Infections, Lungs & breathing clinical trials.
This pilot study tests NOA-001, a treatment given to people with ARDS (a serious lung condition) who are already on a breathing machine. It looks at whether the treatment can improve outcomes in ARDS caused by either non-COVID illnesses or COVID-19.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have ARDS confirmed and started within about 7 days of breathing worsening
- Your breathing failure must not be mainly from heart failure or extra fluid in the lungs
- Chest imaging (X-ray/CT) must show changes in both lungs that can’t be explained by other causes
- You must be on a breathing machine (intubated and mechanically ventilated)
- Enrollment must happen within 96 hours after starting the breathing machine
- Your oxygen levels on the ventilator must fall within a specified range (PaO2/FiO2 50–200 at enrollment)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at a specific breathing event (“avalanche phenomenon”) when the lungs are opened in people with early, moderate-to-severe ARDS. The goal is to understand what’s happening in the lungs and whether it can guide better care.
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
This trial tests a new drug called LEAF-4L6715 to see if it helps people with severe acute respiratory distress syndrome (ARDS), a serious lung condition. If you are on a breathing machine and meet the criteria below, you may be able to join.
This study tests whether giving nitric oxide gas through a breathing tube helps people with a lung condition called ARDS (acute respiratory distress syndrome) recover and leave the intensive care unit sooner. It may help some patients with mild-to-moderate cases who need a ventilator and a central line.
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Hear when a new Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.