Clin2
NCT05801224Possibly a fitRecruiting

Inhaled nitric oxide for lung injury in intensive care

Acute Respiratory Distress SyndromeVentilation Perfusion Mismatch

Part of Lungs & breathing clinical trials.

This study tests whether giving inhaled nitric oxide gas helps improve lung function in patients on a breathing tube with mild to moderate acute lung injury (ARDS). Participants will receive standard care plus the study gas, and the team will use special imaging to see how the lungs respond.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
70 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be 18-80 years old and on a breathing tube (ventilator) in the intensive care unit.
  • You must have a diagnosis of mild to moderate acute respiratory distress syndrome (ARDS) with a specific oxygen level range.
  • You must have an arterial line (small tube in an artery) and a central line (small tube in a large vein) in place.
  • You cannot have severe lung disease, sickle cell disease, or certain enzyme deficiencies (G6PD or cytochrome b5 reductase).
  • You cannot be pregnant or less than 6 weeks after giving birth.
  • You cannot have unstable blood pressure or recent changes in ventilator settings.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure

This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.

Los Angeles, California
NCT06950294Recruiting· Early Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator

This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.

Boston, Massachusetts
NCT06675435Not yet recruiting
Inhaled nitric oxide for severe obesity with breathing failure

This trial tests whether inhaled nitric oxide can help people with severe obesity who are on a breathing machine because their lungs aren't getting enough oxygen. It aims to see if this treatment improves oxygen levels and recovery.

Boston, Massachusetts
NCT06702553Recruiting· Phase 3
Nitric oxide to reduce support after heart surgery

This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.

Boston, Massachusetts
NCT07617298Not yet recruiting
Inhaled nitric oxide for lung function in ARDS patients on breathing support

This study tests whether inhaling nitric oxide gas can improve how well oxygen moves from the lungs into the blood in people with ARDS who are using noninvasive breathing support like a CPAP or high-flow nasal oxygen. It may help doctors understand if this treatment can improve lung function and potentially reduce the need for a breathing tube.

Shanghai
NCT07334873Not yet recruiting
Nitric oxide gas for adults with severe breathing failure

This study tests whether breathing in a special gas called nitric oxide can help people with moderate to severe ARDS (a severe form of lung failure that makes it hard to breathe). The gas is used to improve oxygen levels and may help patients on a ventilator recover.

Guangzhou, Guangdong

Hear when a new Acute Respiratory Distress Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.