Safety and benefit of injecting fibroblast cells in leg amputees’ skin
Part of Injuries & trauma clinical trials.
This Phase 2 study tests whether injecting a patient’s own (autologous) fibroblast cells into the end of a transtibial (below-knee) amputation is safe and may improve outcomes. You may qualify if you have a certain type of prosthesis timing and healthy skin on the stump, and you can follow frequent visit and wound-care instructions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 75 years old
- Have a transtibial (below-knee) amputation
- Use your prosthesis near the limb recently (within 3 months) or have had a prosthesis “osteointegration” for at least 1 month
- Have healthy skin on the end of the amputation site and no significant, active skin problems or non-healing wounds
- Not have certain wound problems (for example, no large ulcers, no ulcers that can’t tolerate a small safety margin, and no deep tissue erosion)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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