Stem cell injection for severe leg circulation problems
Part of Heart & circulation clinical trials.
This study tests whether stem cells taken from donated fat tissue are safe to inject into people with severe leg circulation problems (critical limb ischemia). It aims to see if the treatment is well tolerated and may help improve blood flow and reduce pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 18 or older
- Have critical limb ischemia: either rest pain or non-healing sores on the leg or foot, plus low blood pressure or low oxygen in the affected limb
- Not a candidate for surgery or angioplasty (or had such treatment but still have severe ischemia)
- Life expectancy longer than 6 months
- If of childbearing age, must use effective contraception and have a negative pregnancy test
- No active cancer in the past 5 years (except cured basal cell skin cancer or early-stage melanoma), no allergy to local anesthetics, no immunosuppressive therapy, and no major amputation expected within a month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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