Valve procedure trial for severe leaking aortic valve
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies a less invasive heart valve procedure that places a new valve through a catheter, to treat severe leakage of the aortic valve. It may help people who have symptoms or heart enlargement and who are at higher risk for open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic valve leakage, and you have symptoms or your heart measurements are below certain cutoffs.
- Your echocardiogram/heart scan results fit specific size targets for the valve opening and nearby valve pathway.
- Your average valve pressure measurements are below 20 mmHg, and the valve opening size is within a set limit.
- You are age 60 or older, and you have higher risk for surgery (or you refuse surgery).
- You can take required heart medicines (including aspirin, clopidogrel, warfarin if used, and contrast dye).
- You do not have major exclusions like very low pumping function, recent heart attack, limited life expectancy, or certain artery/blockage patterns.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies people with severe aortic valve disease who will receive a catheter-based valve replacement (TAVR). It aims to check how well this approach works for fixing a narrowed or leaky aortic valve, and to monitor outcomes afterward.
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This study looks at how safe and effective an emergency heart valve replacement is for people with severe aortic stenosis who are in critical condition. It may help if you have severe symptoms like shock or unstable chest pain that need urgent treatment.
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