Danazol for low blood counts in some people with cirrhosis
Part of Blood & lymphatic, Digestive system clinical trials.
This Phase 2 study tests danazol to improve low blood counts (low white blood cells and/or low platelets) in people with certain types of cirrhosis. It also looks at who may benefit, especially those with specific inherited blood-telomere changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 or older and able to sign consent
- Have cirrhosis that is “compensated” (Child-Pugh class A, or certain people with class B)
- Have documented low blood counts (white blood cells and/or platelets) on two blood tests at least 3 months apart within 6 months of starting the study
- Have one qualifying telomere-related result: a specific gene variant or shortened telomere length on a specific blood test
- If you can become pregnant: agree to effective birth control (or abstain) and have a negative pregnancy test within 72 hours before starting
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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