Testing dotinurad vs allopurinol for people with gout
Treatments studied
Part of Bones, joints & muscles, Genetic & congenital, Hormones & metabolism clinical trials.
This study compares a new gout medicine called dotinurad to the common medicine allopurinol. It is for people who have had gout for at least a year, have had at least 2 gout attacks in the last year, and are already taking a stable dose of allopurinol but still have high uric acid levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with gout for at least 1 year.
- You have had at least 2 gout flares in the last 12 months.
- You are currently taking allopurinol (at least 300 mg daily, or 200 mg if you have kidney problems) for at least 3 months and are on a stable dose.
- Your uric acid level is 6.5 mg/dL or higher (checked twice during screening).
- You do not have a history of kidney stones in the last year, cancer in the last 5 years (except some skin cancers), or certain allergies to study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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