Clinical trials
Gout clinical trials
Below are recruiting gout clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
Birmingham, AlabamaAges 18 years+ - NCT07145229RecruitingPhase 2
Testing a new drug for acute gout flares
This trial tests a new medication, ABP-745, for people having an acute gout flare. It aims to see if the drug is safe and helps reduce pain and inflammation.
Peoria, ArizonaAges 18–70 - NCT07346079RecruitingPhase 4
Corticotropin gel for acute gout flares
This study tests two doses of a medicine called Purified Cortrophin Gel for people having a gout flare that started in the last 5 days. It might be an option if other treatments haven't worked or aren't safe for you.
Boston, MassachusettsAges 18–90 - NCT06863701RecruitingPhase 3
Combination therapy for acute gout flare
This trial tests a combination of two medicines, etoricoxib and betamethasone, for quickly treating a painful gout flare. It is for people who have had gout before and whose current attack started within two days.
Mexico CityAges 18 years+ - NCT06971146Recruiting
Nurse-led telehealth for gout management
This trial tests whether nurse-led telehealth visits can help people with gout maintain healthy urate levels. If you have gout and are already on medication like allopurinol, this study may offer a convenient way to manage your condition from home.
AarhusAges 18 years+ - NCT07367971RecruitingPhase 1
ABP-671 interaction study for gout patients
This study tests how a new drug, ABP-671, interacts with allopurinol (a common gout medicine) in people with gout. It is looking for participants with normal or moderately reduced kidney function.
Cary, North CarolinaAges 18–75 - NCT07388498RecruitingPhase 3
Study of pegloticase with methotrexate for uncontrolled gout
This trial tests a new way of giving pegloticase (a drug that breaks down uric acid) by injection under the skin, combined with methotrexate, to see if it works better for people with uncontrolled gout. It might help if you have painful flares that don't go away with usual treatments.
Birmingham, AlabamaAges 18 years+ - NCT07362355RecruitingPhase 2
New gout pill combined with febuxostat for high uric acid
This trial tests an experimental tablet (SHR4640) added to the standard gout medicine febuxostat (40 mg daily) for people whose uric acid remains too high despite febuxostat alone. The goal is to see if the combination lowers uric acid more effectively and safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07089888RecruitingPhase 3
Dotinurad vs allopurinol for gout with lumps
This trial is testing a new gout medication, dotinurad, compared to the standard treatment allopurinol for people with tophaceous gout (gout that causes hard lumps). It aims to see if dotinurad is better at reducing uric acid and shrinking those lumps.
Birmingham, AlabamaAges 18–75 - NCT06674109RecruitingPhase 4
Testing a diabetes drug for gout prevention
This study tests if a type 2 diabetes medication (SGLT2 inhibitor) can help people with frequent gout flares. It aims to lower uric acid levels and reduce flare-ups.
Boston, MassachusettsAges 18–80 - NCT07587684RecruitingPhase 1
Testing IN026 for Hard-to-Treat Gout
This study tests a new drug called IN026 for people with refractory gout—gout that doesn't respond well to current treatments and causes severe symptoms. The goal is to see if IN026 can lower uric acid levels and reduce gout attacks.
WuhanAges 18–75 - NCT07089875RecruitingPhase 3
Testing dotinurad vs allopurinol for people with gout
This study compares a new gout medicine called dotinurad to the common medicine allopurinol. It is for people who have had gout for at least a year, have had at least 2 gout attacks in the last year, and are already taking a stable dose of allopurinol but still have high uric acid levels.
Birmingham, AlabamaAges 18–75 - NCT07535034RecruitingPhase 2
Testing Dotinurad for Gout in People Who Can't Take Other Medications
This trial tests a new drug called dotinurad for gout patients whose standard medications either don't work or cause side effects. Dotinurad works differently by helping your body get rid of uric acid (the substance that causes gout attacks), and the study will see if it safely lowers uric acid levels.
Granada Hills, CaliforniaAges 18–75 - NCT04875702RecruitingPhase 4
Compare urate targets to reduce gout attacks or symptoms
This study compares two different treatment goals for a blood level called urate in people with gout. The goal is to see which approach lowers gout flares better while helping people feel better.
South Birmingham, AlabamaAges 18–90 - NCT05546593Recruiting
Ultrasound check for joint and tendon problems in gout
This study uses ultrasound to look for hidden changes in joints and tendons in people who have gout. It may help doctors better understand what ultrasound can show in gout, but it doesn’t sound like it’s testing a new medicine.
Boulogne-Billancourt, APHPAges 18 years+ - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT06298071RecruitingPhase 1
Peguricase with methotrexate for uncontrolled gout
This early-phase trial tests a new injectable medication (Peguricase) combined with methotrexate to lower uric acid in people with gout that standard pills haven't controlled. You would first take a low dose of methotrexate to check your tolerance, then receive Peguricase infusions while stopping your usual gout medications.
Bengbu, AnhuiAges 18–70 - NCT06534554Recruiting
Improving gout care after an emergency room visit
This study looks at ways to improve how gout is managed after a visit to the emergency room. It aims to help you get better follow-up care and prevent future flares.
Birmingham, AlabamaAges 18–99 - NCT06622603RecruitingPhase 4
Testing lower doses of febuxostat in well-controlled gout
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
Seongnam-si, Gyeonggi-doAges 19–79 - NCT06629376RecruitingPhase 1
Testing a new gout drug for safety and effect on uric acid
This trial tests an experimental drug, SSS11, to see if it is safe and how it affects uric acid levels in people with gout and high uric acid. You may not take other gout medicines during the study.
ShanghaiAges 18–65 - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT06966635RecruitingPhase 4
Potassium citrate for gout treatment
This study tests whether a potassium citrate tablet can help people with gout lower uric acid and prevent flares. It is for adults on stable gout medication who are not having a current flare.
ShanghaiAges 18–70 - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Little Rock, ArkansasAges 18 years+ - NCT07343336Recruiting
Study of gout in French Polynesia
This study looks at gout in people of Polynesian ancestry to learn more about its causes and how it affects people. It may help improve diagnosis and treatment for this community.
Faa'aAges 18–75
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Gout trials by city
Studies with a site in or near these metro areas.
Gout trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for gout?
- Yes. Clin2 currently lists 44 recruiting gout studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gout trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gout trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.