Testing heart scan measurements in severe aortic valve narrowing
Part of Heart & circulation clinical trials.
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic valve stenosis and are a candidate for transcatheter valve replacement
- Your heart pumping strength (left ventricular ejection fraction) is above 55%
- You are older than 65
- You have no known intolerance to adenosine (a medication used during testing)
- Your heart rhythm history does not include slow heart rates (bradycardia) or heart wiring blocks (AV block)
- Your moderate coronary artery narrowings have an FFR above 0.8 (your doctor’s test result)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
This Phase 2 trial uses a PET scan to study how local inflammation inside the heart affects the heart’s electrical wiring after a minimally invasive aortic valve procedure. The results may help doctors better predict or prevent rhythm and conduction problems after treatment.
This study is testing a new way to monitor blood flow and heart function during a valve replacement procedure. It may help doctors track how well the heart is pumping.
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
This study uses imaging to measure heart scarring in people with aortic stenosis, a condition where the heart valve is narrowed. It aims to better understand how scarring affects long-term outcomes.
Hear when a new Aortic Valve Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.