Clin2
NCT04893564Possibly a fitRecruiting

Testing blood DNA after 6 months of Waldenström treatment

Waldenstrom's DiseaseWaldenstrom Macroglobulinemia

Treatments studied

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study looks at a blood test called circulating tumor DNA, measured after 6 months of treatment, to see how well it predicts outcomes in people with Waldenström macroglobulinemia. It may help doctors better judge who is responding and who may need treatment adjustments earlier.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with Waldenström macroglobulinemia (WM).
  • Your care for WM happens in a hospital/center in the North-Western region.
  • You need to start treatment now or you are starting a new round of treatment (first-line or later-line).
  • You are willing and able to sign consent to join the study and share needed information/blood samples.
  • You have health coverage through the social insurance system.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05911802Recruiting
Study of outcomes in people with Waldenström’s disease

This study looks at medical records to understand what outcomes happen in people with Waldenström’s disease and how well certain factors predict those outcomes. It’s mainly about using past and planned follow-up data, which may help improve care for future patients.

Amiens
NCT04898647Recruiting
Study of blood thickness in Waldenström’s disease

This study looks at “hyperviscosity,” meaning very thick blood, in people with Waldenström macroglobulinemia (WM). Your results may help doctors better understand who needs treatment and what tests should be used, even if thick blood is not found.

Amiens
NCT07231952Recruiting· Phase 2
Study of pirtobrutinib, venetoclax, and rituximab for Waldenström's macroglobulinemia

This trial tests a combination of three targeted drugs for people with untreated Waldenström's macroglobulinemia (WM), a rare blood cancer. The drugs aim to shrink tumors and lower the abnormal antibody (IgM) that causes symptoms, potentially offering a new first-line treatment option.

Boston, Massachusetts
NCT00923507Recruiting
Study of blood cancers’ natural course and next treatment needs

This study follows people with certain slow-growing blood cancers (CLL/SLL, LPL/WM, and related conditions) to understand how they progress and what leads to needing treatment. It may help doctors predict changes over time and plan care more effectively.

Bethesda, Maryland
NCT07548450Not yet recruiting· Phase 2
Two targeted drugs for relapsed Waldenstrom macroglobulinemia

This trial tests a combination of two targeted therapies for Waldenstrom macroglobulinemia that has come back or not responded to previous treatment. The combination aims to attack the cancer cells in two different ways and may be more effective than either drug alone.

Salt Lake City, Utah
NCT06510491Recruiting· Phase 2
Epcoritamab for relapsed Waldenstrom macroglobulinemia

This trial tests epcoritamab, an immunotherapy that helps your immune system attack cancer cells, for people with Waldenstrom macroglobulinemia (WM) whose disease has gotten worse or who couldn't tolerate previous treatments. It's for those who've already tried a BTK inhibitor (like ibrutinib or zanubrutinib) and an anti-CD20 antibody (like rituximab).

Boston, Massachusetts

Hear when a new Waldenstrom Macroglobulinemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.