Azacitidine or decitabine plus venetoclax for AML after prior failure
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial studies whether adding venetoclax to either azacitidine or decitabine can treat acute myeloid leukemia (AML) when earlier “hypomethylating” treatment has stopped working. You might be a candidate if you’ve already tried azacitidine or decitabine for a related blood condition and it failed, and you meet the health-safety limits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and willing to sign informed consent
- You have AML confirmed by standard blood cancer criteria
- You’ve already tried azacitidine or decitabine for a related blood condition, and it failed
- Your AML treatment plan before this study must be new (no prior AML treatment)
- Your heart, lung, kidney, liver, and general stamina meet the study safety cutoffs
- You can take venetoclax by mouth and you agree to pregnancy prevention during and after treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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