Lower-dose radiation for metastatic cancer with an ATM mutation
Part of Brain & nervous system, Cancer, Genetic & congenital clinical trials.
This trial tests whether giving a lower dose of radiation can help control metastatic tumors that carry a specific genetic change in the ATM gene. It may reduce side effects by using less radiation, while still aiming to keep the tumor under control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (18 or older) with confirmed cancer that has spread to at least one place that needs palliative (comfort-focused) radiation
- Your tumor—or your body—has a confirmed harmful ATM genetic change (called a pathogenic ATM mutation)
- Your overall health/activity level is fairly good (ECOG 0–2)
- Your expected life expectancy is at least 6 months
- You can safely receive radiation: you’re not pregnant or breastfeeding, and you can follow effective birth control during treatment if applicable
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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