Checking RNA markers in blood and muscle in muscle disease
Part of Bones, joints & muscles, Brain & nervous system, Genetic & congenital clinical trials.
This study looks for tiny RNA “signals” in blood (and sometimes urine) and compares them with muscle samples in people with myotonic dystrophy (DM1 or DM2) and healthy controls. The goal is to find biomarkers that may help track the disease over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have myotonic dystrophy type 1 (DM1) or type 2 (DM2), or you are a non-DM control
- Your DM1/DM2 status is confirmed by genetic testing and/or doctor’s clinical diagnosis
- You can provide written informed consent (or assent if you’re a minor with parent/guardian consent)
- Your age must fit the study parts: blood/one-time collection from age 5+, repeated measures from age 14+ (DM1), and biopsy from age 18–65
- You must not have certain health conditions like immunosuppression, bleeding/clotting problems, or known liver or kidney disease
- You must not be pregnant if you plan to have a muscle biopsy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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