Drug-coated balloon for severe leg artery blockage in lower legs
Part of Heart & circulation clinical trials.
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have severe, long-lasting poor blood flow in a leg that affects the foot/limb (described as Rutherford category 4 or 5) lasting more than 2 weeks.
- You can provide written consent and will be able to return for follow-up visits.
- Your pregnancy test is negative (for people who can become pregnant), and you are not breastfeeding.
- Your blockage is in specific lower-leg (below-knee) arteries and is a new or non-stent-recurrent blockage, with severe narrowing (about 70% or more).
- Your kidneys are working well enough (not on dialysis, and recent kidney function is not too low), and you do not have certain serious exclusions like recent major infection or recent major stroke/heart attack.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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