Clinical trials
Peripheral Arterial Disease clinical trials
Below are recruiting peripheral arterial disease clinical trials, each written for real people, not researchers. We’re tracking 215 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT04903912Recruiting
Study of people with blocked blood vessels or aneurysms
This registry study follows people with peripheral artery disease (blocked leg arteries), certain carotid artery narrowing, or an abdominal aortic aneurysm. It may help doctors better understand these conditions and improve care over time.
NaplesAges 18–90 - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05391815Recruiting
Observational study of endovascular treatment for blocked leg arteries
This is a real-world observational study that follows people who get minimally invasive procedures to treat blocked arteries in the lower abdomen and pelvis. It aims to understand how well these treatments work in the middle and long term.
ShanghaiAges 18–80 - NCT04188808Recruiting
Study comparing patients with artery disease before surgery
This study looks at people with blocked leg arteries who are having planned (elective) open surgery for symptoms like leg pain when walking or at rest. It aims to better understand what to expect in these patients and how to compare outcomes between groups.
GothenburgAges Any age - NCT05894863Recruiting
Smart stent for severe leg artery blockages
This trial studies a new “smart” stent placed in the thigh-to-knee artery to treat significant blockages. It may help improve blood flow to the foot, and you would be followed closely to see how well the stent works over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05701293Recruiting
RenZan stent check for leg artery narrowing
This trial follows how well the RenZan stent works and how safe it is for people with blocked or badly narrowed thigh-to-knee leg arteries. It may help by improving blood flow and adding careful monitoring to see how outcomes compare over time.
SienaAges 18 years+ - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients
This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06250790Recruiting
Heart Artery Check for Leg Artery Disease Patients
This trial uses a special CT scan (coronary CTA with HeartFlow analysis) to look for hidden blockages in the heart arteries of people who recently had a leg artery procedure. It may help detect heart problems early so they can be treated.
RigaAges 50 years+ - NCT06067789Recruiting
Testing spinal vs. general anesthesia for leg blood flow surgery
This study tests a new way to give anesthesia during leg surgery to improve blood flow. It aims to see if spinal anesthesia works better than general anesthesia for recovery and comfort.
Ottawa, OntarioAges 18 years+ - NCT04912323Recruiting
Drug dissolving stent for blocked below-knee arteries
This trial studies a drug-eluting dissolving scaffold placed in blocked arteries below the knee to improve blood flow. It may help people whose leg circulation problems are severe enough to limit walking or threaten the limb, but only if their blockages fit specific imaging and procedure requirements.
GrazAges 18–90 - NCT07850349Recruiting
Automatic ankle blood pressure test for leg artery disease
This study tests a new automated way to measure the blood pressure in your ankles, which helps doctors check for narrowed leg arteries. It is a pilot study, meaning it looks at whether this automatic method works well and is comfortable, which could make testing easier in the future.
HullAges 18 years+ - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT07811024Recruiting
Strolimus-coated balloon for blocked coronary arteries
This study tests a balloon coated with a drug that may help keep arteries open after they've been cleared, especially for people with a narrowing inside a previously placed stent or in a small heart artery. It's a first-time-in-humans study to check if the treatment is safe and works.
TashkentAges 21 years+ - NCT06022653Recruiting
Aorta and peripheral artery disease registry
This study collects information from people who have had treatment for aorta or peripheral artery disease at Asan Medical Center since 2011. It helps researchers understand how patients are doing over time.
SeoulAges 19 years+ - NCT07796217RecruitingPhase 4
Comparing blood thinners after a heart attack
This study compares two ways to lower the chances of another heart attack: taking the standard medicine (clopidogrel) versus taking a combination of aspirin and a lower dose of a blood thinner (rivaroxaban). If you join, you'll be assigned to one of these options to see which works better for people like you.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+ - NCT07655206Recruiting
Home exercise for moderate to severe PAD
This study tests whether doing simple leg exercises at home with a small, portable pedal machine can help improve walking and blood flow in people with moderate-to-severe PAD. It's for people who cannot or prefer not to join a hospital-based exercise program.
Lévis, QuebecAges 18 years+ - NCT07614386Recruiting
Radial artery access outcomes in heart and vessel procedures
This registry collects data from patients undergoing heart or blood vessel procedures using a small artery in the wrist (radial or ulnar artery) for access. Researchers track outcomes to better understand the safety and effectiveness of this approach.
Mersin, MezitliAges 18 years+ - NCT07613840Recruiting
Personalized Blood Clot Prevention After Leg Artery Surgery
This study tests a personalized approach to prevent blood clots in patients who have had surgery to repair blocked arteries in their legs. Researchers want to find the best blood-thinning medication for each individual to reduce serious complications while keeping you safe.
Boston, MassachusettsAges 18 years+
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Peripheral Arterial Disease trials by city
Studies with a site in or near these metro areas.
Peripheral Arterial Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for peripheral arterial disease?
- Yes. Clin2 currently lists 215 recruiting peripheral arterial disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral arterial disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral arterial disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.