Back pain trial using your own stem cells in discs
Part of Bones, joints & muscles, Pain clinical trials.
This Phase 2 trial tests whether injecting your own stem cells into a few back discs can reduce chronic low back pain that has not improved with standard treatments. It may help by targeting disc-related (degenerative) wear seen on MRI, but it requires detailed MRI and blood test screening.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic low back pain for at least 6 months despite usual care (like physical therapy and common pain medicines).
- Your MRI shows moderate disc disease in up to 3 levels, and the disc ring is still intact.
- Your average pain is more than 40 out of 100 on a pain scale (VAS) at the start of screening.
- You must stop certain pain medicines briefly before screening (NSAIDs for 2 days; painkillers for 24 hours).
- You must be able to have MRI and tolerate local numbing medicine; you also cannot have certain back conditions (like disc herniation with sciatica).
- If you could become pregnant, you need a negative pregnancy test and must use reliable birth control during treatment and for 24 months after the stem cell injection stops; breastfeeding must be stopped during treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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