Talazoparib plus ZEN003694 for recurrent ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This Phase 2 trial tests whether combining ZEN003694 with talazoparib can slow or shrink recurrent ovarian, fallopian tube, or primary peritoneal cancer. It is designed for people who have already been treated with a PARP inhibitor before, and it may help if that cancer comes back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman age 18 or older and can sign consent.
- Your cancer is proven in pathology as ovarian, fallopian tube, or primary peritoneal cancer, and it has come back.
- You have previously received a PARP inhibitor (PARPi) for treatment or maintenance.
- Your cancer must have measurable tumor spots on scans (RECIST 1.1).
- Your recent blood tests and organ function meet safety limits (blood counts, liver, kidneys, and clotting).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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