Alzheimer’s scan study for people with higher body weight
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 40 to 60 (any race, male or female).
- Your memory testing is not showing dementia: MMSE 25+ or CDR 0.
- You can safely have MRI scans and lie still for the scan time.
- You are willing to have two PET scans with radioactive tracers (including PiB and flortaucipir).
- You have a qualifying body size: BMI 25 to under 45, or BMI 18.5 to under 25, and your body circumference is under 165 cm to fit the scanner.
- You must match one of the study’s blood-sugar/insulin categories (low/normal vs higher sugar patterns), and you should not already have diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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