Tofacitinib vs methotrexate for active Takayasu’s arteritis
Treatments studied
Part of Heart & circulation, Skin clinical trials.
This trial compares two medicines—tofacitinib and methotrexate—to see which works better for controlling active Takayasu’s arteritis. It also looks at safety in people with this condition who need treatment right now.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Takayasu’s arteritis using standard ACR criteria
- You’re 18 to 65 years old
- Your Takayasu’s arteritis must be “active” based on a disease-activity checklist
- You agree to use birth control during the study and pregnancy tests must be negative
- You can and will sign the informed consent
- You do not have certain major health problems (like severe heart, serious liver/kidney issues, or uncontrolled high blood pressure)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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