Chemotherapy and radiation before surgery for colorectal cancer with belly lymph node spread
Part of Cancer, Digestive system clinical trials.
This trial is testing whether combining chemotherapy and radiation therapy before surgery can help people with left-sided colon or rectal cancer that has spread to certain lymph nodes in the belly. The goal is to remove all cancer during surgery and possibly improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You are generally well and able to do daily activities without much help (ECOG 0-1).
- You have been diagnosed with left-sided colon or rectal cancer.
- Your cancer has spread only to specific lymph nodes in the belly (para-aortic nodes) as seen on a PET-CT scan, and not to other organs or distant areas.
- You are expected to be able to have surgery to remove all visible cancer.
- You do not have other serious illnesses like recent heart attack, severe heart disease, or active lung infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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