Dolutegravir levels in people with HIV and depression
Treatments studied
Part of Mental health clinical trials.
This trial studies how the HIV drug dolutegravir works in people who also have depression. Participants will receive an antidepressant called fluoxetine to see how it affects the HIV treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and living with HIV.
- You are willing to take or continue your HIV medication (dolutegravir-based).
- You have current symptoms of depression and are willing to take fluoxetine, an antidepressant.
- You have no immediate risk of suicide, no severe mental health conditions like schizophrenia or bipolar disorder, and no history of bad reaction to fluoxetine.
- Your kidney and liver function are within acceptable levels.
- You are not pregnant, planning to get pregnant, or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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