Brain scan study in severe sleep apnea without CPAP
Part of Brain & nervous system, Lungs & breathing clinical trials.
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 to 75 years old
- Have severe obstructive sleep apnea (AHI greater than 30 events per hour) and not be on CPAP
- If you are not in the sleep apnea group: you must have no sleep apnea (AHI less than 15) and no excessive daytime sleepiness (Epworth score less than 11)
- Be able to safely do an MRI scan (no metal in your body that is unsafe for MRI, and you can tolerate the scanner; pregnancy must be ruled out)
- Not have certain neurologic or breathing problems, and avoid medicines that can affect MRI brain signals (or discuss your meds with the team)
- Be right-handed (left-handed people are excluded) and have no major current mood or certain mental health conditions based on questionnaire results
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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