Steroids to treat acute pancreatitis in the ICU
Treatments studied
Part of Digestive system clinical trials.
This Phase 2 study tests whether corticosteroids (steroid medicines) can improve outcomes for adults with severe acute pancreatitis in the intensive care unit. It’s meant to see if steroids help when the pancreas inflammation is serious.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have acute pancreatitis, with a blood test (lipase) at least 3 times higher than normal.
- You are already admitted to the ICU or you are expected to be admitted to the ICU.
- Your illness severity is high (SOFA score 3 or higher, or 3+ points above your usual baseline).
- You do not have a known diagnosis of autoimmune pancreatitis.
- You are not pregnant and can safely take the study steroid medicine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving a steroid called hydrocortisone before and after surgery to remove part of the pancreas can help patients recover better. It aims to reduce complications and improve outcomes.
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
This study tests whether a corticosteroid (a type of anti-inflammatory medicine) can help people with severe breathing problems or serious infections who have a specific 'hyperinflammatory' pattern. If you are in the ICU on a ventilator, this trial may be an option for you.
This trial compares two common steroid medicines, hydrocortisone and prednisolone, to see which works better for people with severe community-acquired pneumonia. It aims to find the best treatment to help you recover faster.
This trial tests whether adding anti-inflammatory medicine (steroids) to usual care helps people with severe pneumonia recover faster. It only includes patients who are seriously ill in the ICU, and the goal is to find the best way to reduce lung inflammation and improve outcomes.
This study tests whether giving a personalized dose of steroids (anti-inflammatory medicine) early can help people with severe pneumonia-related breathing failure recover faster. It compares different steroid doses based on your body's inflammation and immune response.
Hear when a new Pancreatitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.