Treatment
Hydrocortisone clinical trials
We’re tracking 44 recruiting studies that include Hydrocortisone, each written for real people, not researchers, below.
Recruiting studies
- NCT07037043RecruitingPhase 3
Steroid medicines for high-risk heart surgery patients
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
AmiensAges 18 years+ - NCT03760835RecruitingPhase 4
Once-daily hydrocortisone for adults with congenital adrenal hyperplasia
This trial studies whether a once-daily hydrocortisone tablet works as well as standard steroid treatment for adults with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. It aims to improve how safely and conveniently hormone replacement is taken each day.
NaplesAges 18 years+ - NCT04591990RecruitingPhase 3
Hydrocortisone and vasopressin for shock after cardiac arrest
This Phase 3 trial tests whether hydrocortisone plus vasopressin (or related hormone treatments) can improve shock in adults after a resuscitated cardiac arrest. It targets people who remain very low in blood pressure despite fluids and need strong IV medicines to maintain blood pressure.
AmiensAges 18 years+ - NCT05435781RecruitingPhase 4
Hydrocortisone added during stress in people on low-dose prednisolone
This study tests whether adding supplemental hydrocortisone during stressful events can prevent problems in people who develop adrenal insufficiency from long-term prednisolone. It is meant to see if “stress dosing” is safer and helps the body respond to stress.
AarhusAges 50 years+ - NCT02735707RecruitingPhase 3
Adaptive trial for severe pneumonia care in intensive care
This study tests ways to improve treatment for adults with severe pneumonia that lands them in the ICU, adjusting the plan as results come in. It may help your care team find better treatments for lung infection and breathing/heart support needs.
Jacksonville, FloridaAges 18 years+ - NCT06381661RecruitingPhase 2
Personalized treatment for sepsis in children and adults
This trial is testing several different treatments to find the best one for each person with sepsis. It looks at specific 'treatable traits' like inflammation, blood clotting problems, or immune system issues to match you with the right therapy. The goal is to improve recovery and survival.
DijonAges 9 months+ - NCT07154849RecruitingPhase 4
Preventing shivering after abdominal surgery with two IV drugs
This trial tests two intravenous medicines—hydrocortisone and dexmedetomidine—to see which one works better at preventing shivering after abdominal surgery. It may help you stay comfortable and recover more smoothly.
CairoAges 18–65 - NCT06930456Enrolling by invitation
Comparing two drugs to prevent low blood pressure during spinal anesthesia
This study tests if giving hydrocortisone (a type of steroid) or ondansetron (an anti-nausea drug) before spinal anesthesia can better prevent low blood pressure during surgery for your belly or lower leg.
Port Said, Port Said GovernorateAges 21 years+ - NCT05008146RecruitingEarly Phase 1
Brain imaging study for cocaine use disorder interactions
This early-phase study uses brain imaging to understand how cocaine use disorder affects brain function. It may help researchers learn more about brain pathways involved in craving and treatment targets.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06895473RecruitingPhase 2
Spinal injection to prevent nerve side effects from CAR-T therapy
This trial tests if a spinal injection of three common chemotherapy drugs can reduce or prevent serious brain and nerve side effects in people receiving CAR-T cell therapy for cancer.
Portland, OregonAges 18 years+ - NCT03401398RecruitingPhase 3
Hydrocortisone for children with septic shock in the ICU
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
Tucson, ArizonaAges 1 month–17 years - NCT05160506RecruitingPhase 2
Steroids to treat acute pancreatitis in the ICU
This Phase 2 study tests whether corticosteroids (steroid medicines) can improve outcomes for adults with severe acute pancreatitis in the intensive care unit. It’s meant to see if steroids help when the pancreas inflammation is serious.
Boston, MassachusettsAges 18–99 - NCT05193396RecruitingPhase 4
Hydrocortisone trial for adrenal symptoms after stopping steroid pills
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
AarhusAges 50 years+ - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT06892197RecruitingPhase 4
Comparing two steroids for severe pneumonia
This trial compares two common steroid medicines, hydrocortisone and prednisolone, to see which works better for people with severe community-acquired pneumonia. It aims to find the best treatment to help you recover faster.
Rønne, BornholmAges 18 years+ - NCT06892210RecruitingPhase 4
Steroid comparison for COPD flare-ups
This trial compares two common steroids, hydrocortisone and prednisolone, to see which works better for treating COPD flare-ups. It may help you recover faster from a sudden worsening of your breathing.
Rønne, BornholmAges 40 years+ - NCT06982183RecruitingPhase 4
Propranolol and hydrocortisone effects on military performance
This trial studies how two medications—propranolol (a beta blocker often used for anxiety) and hydrocortisone (a steroid)—affect performance on military tasks. It aims to understand if these drugs help or hinder how soldiers perform under stress.
Silver Spring, MarylandAges 18–40 - NCT07383103RecruitingPhase 4
Steroid combination for septic shock
This trial tests whether two medicines (hydrocortisone and fludrocortisone) can help people with severe infections that cause dangerously low blood pressure (septic shock). It's for patients who have just been diagnosed and haven't used steroids recently.
Yangzhou, JiangsuAges 18–90 - NCT02691858Recruiting
Hydrocortisone for babies with bowel telescoping after air treatment
This trial looks at whether giving hydrocortisone (a steroid medicine) can improve outcomes for infants with intussusception, a condition where part of the bowel slips into another part. It specifically focuses on babies treated with a non-surgical air method to push the bowel back in place.
CairoAges 3 months–4 years - NCT07612631RecruitingEarly Phase 1
Brain imaging study of alcohol and stress response
This research uses brain imaging to understand how two brain systems—one involved in stress and one involved in reward—interact in people with alcohol use disorder. The goal is to find new ways to help people reduce heavy drinking.
Pittsburgh, PennsylvaniaAges 18–55 - NCT06136650RecruitingPhase 3
Study of a new drug for advanced prostate cancer
This study tests a new oral drug called opevesostat against another standard hormone therapy for men with advanced prostate cancer that has spread and is no longer controlled by a first hormone therapy. It's for men who have not had chemotherapy for this stage and who have not used a PARP inhibitor or chose not to.
Tucson, ArizonaAges 18 years+ - NCT06136624RecruitingPhase 3
Comparing a new drug to standard hormone therapy for advanced prostate cancer
This trial tests a new pill, opevesostat, against other hormone treatments for men with metastatic castration-resistant prostate cancer that has progressed after previous therapies. It aims to see which approach works better.
Orange, CaliforniaAges 18 years+ - NCT06317662RecruitingPhase 2
Adding venetoclax and blinatumomab to chemo for infant leukemia
This trial tests adding two newer medicines (venetoclax and blinatumomab) to standard chemotherapy for infants with a specific type of leukemia. The goal is to see if this combination helps more babies stay cancer-free.
Birmingham, AlabamaAges Up to 12 months - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+
What Hydrocortisone is being studied for
Conditions with recruiting Hydrocortisone studies.
Common questions
- Are there clinical trials studying Hydrocortisone?
- Yes. Clin2 currently lists 44 recruiting studies that include Hydrocortisone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Hydrocortisone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Hydrocortisone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Hydrocortisone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.