Hydrocortisone and fludrocortisone for critical illness hormone shortage
Part of Hormones & metabolism clinical trials.
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and currently in an intensive care unit (ICU)
- Your doctors report a SOFA score of 4 or higher for at least 6 hours
- You can have consent by you, your legal representative, or emergency “deferred” consent
- You must be covered by the social security system or universal health coverage
- You must not have certain excluded conditions (such as septic shock or known chronic adrenal failure)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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