Olanzapine vs mirtazapine for weight loss in advanced cancer
Treatments studied
Part of Cancer, Mental health clinical trials.
This Phase 2 study tests whether the medicines olanzapine or mirtazapine can help people with advanced cancer who are losing weight without trying. It looks at improving unintentional weight loss when standard cancer care is also ongoing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older and able to give informed consent.
- Have advanced cancer confirmed by pathology (tissue tests) or clinical diagnosis.
- Have lost at least 5% of your body weight in the last 3–6 months without it being explained by simple not eating.
- Be expected to live at least 4 months, according to your care team.
- Be able to communicate and follow study steps, including phone check-ins and keeping written weight/activity logs.
- Have liver tests within an acceptable range (not more than twice the usual upper limit).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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