Colchicine to prevent heart disease in adults with type 2 diabetes
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether a daily low-dose of colchicine, a common anti-inflammatory medicine, can help prevent heart attacks and strokes in people with type 2 diabetes who do not yet have heart disease. If it works, it could be a simple addition to your current diabetes care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have type 2 diabetes and take diabetes medications that have not changed in the last 3 months.
- You have at least one of: high blood pressure, high cholesterol, or a body mass index (BMI) of 27 or higher, and no history of heart or blood vessel disease.
- You have not been hospitalized or had a severe infection in the last 2 weeks.
- You are not currently taking corticosteroid or immunosuppressive medications, aspirin, or certain other interacting drugs.
- You have no history of gout attack in the last year, kidney or liver problems, or muscle pain from statins.
- You are not pregnant, breastfeeding, or planning to conceive in the next year, and you are not taking oral contraceptives.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 study tests whether colchicine and a special type of aspirin can lower the risk of future heart attacks, strokes, or other major heart problems in people with type 2 diabetes who have not had a prior heart event. It aims to reduce cardiovascular risk using medicines that may calm inflammation and protect blood vessels.
This study tests whether taking a daily low dose of colchicine, a medicine used for inflammation, can help prevent a first heart attack or other heart problems in people who are at higher risk due to their risk factors. If you qualify, you would be assigned to take either colchicine or a placebo (a pill with no active medicine) to see if it helps keep your heart healthy.
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