Pre-surgery Y-90 treatment to grow future liver volume
Part of Cancer clinical trials.
This trial tests a radiation treatment called Y-90 given before liver surgery for colorectal cancer that has spread to the liver. The goal is to help the liver grow enough for safer, curative surgery, either right away or as part of a two-step operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have colorectal cancer that has spread to the liver, and your care team thinks you may still be able to get curative-intent surgery
- Your doctors expect your “future liver” volume (sFLR) is too low without a procedure like right portal vein embolization (PVE)
- Have finished at least 4 chemotherapy cycles (about 2 months) before entering the study
- Your overall health should be good enough for surgery (function tests such as ECOG 0–1 and adequate stamina/strength) and your surgeon says you can proceed
- Have blood tests that are safe for treatment and surgery (bilirubin not too high, platelets not too low, albumin not too low)
- You must be able to read and consent in English, and you must be able to provide written informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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