Yttrium-90 therapy before surgery for colorectal cancer that spread to the liver
Part of Cancer clinical trials.
This trial tests a treatment called radioembolization (yttrium-90) given before surgery for colorectal cancer that has spread to the liver. It aims to shrink the liver tumors so that surgery becomes safer and more effective, and it also looks at immune markers and dosimetry to personalize the treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have colorectal cancer that has spread to the liver, and surgery is possible but not straightforward because of the size, location, or number of tumors.
- Any other spread of cancer must be limited and treatable with local treatments (like radiation or surgery).
- You should be generally active (able to do light work) and expected to live at least 3 months more.
- Your liver and kidney function must be good, with normal bilirubin and specific lab values.
- You must not have had radiation to the liver before, and you must not have serious diseases like uncontrolled infections or other cancers in the past 5 years (except minor skin or early-stage cancers).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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