PRF gel in spine surgery to reduce nerve pain after herniation
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 or older and can sign consent for the study
- You have a confirmed lumbar (lower back) disc herniation causing nerve pain (radiculopathy) and are scheduled for surgery
- You are covered by social security health insurance
- If you can become pregnant: you must use reliable birth control and have a negative pregnancy test at the start
- You have never had prior lumbar spine surgery and this is not a different type of herniation (not non-lumbar)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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