Brain imaging study testing mavoglurant in alcohol risk
Part of Brain & nervous system, Mental health clinical trials.
This early-stage study uses brain scans to understand how brain signaling tied to alcohol vulnerability works, and it tests mavoglurant, a medicine that blocks a brain receptor. Results may help researchers learn why some people are more vulnerable to alcohol problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–45 years old
- Your IQ is estimated to be above 70, and you can follow all study instructions
- You do not have major brain or nervous system problems (like epilepsy) and no serious head injury recently
- Your MRI is safe for you (no metal/implants in your body and you can handle being in the scanner)
- You test negative for alcohol and drugs (and for pregnancy if you could become pregnant) on the scan day
- You do not currently have psychosis or ongoing major mood/anxiety problems, and you have no alcohol or substance use disorder that is severe (and you must not have recent withdrawal/craving issues)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
This study tests whether a medication called disulfiram (Antabuse) can help people with alcohol use disorder (AUD) feel less anxious when they stop drinking. Researchers will also use brain scans (MRI) to look at how the brain changes during early abstinence.
This early-phase study looks at how the brain’s opioid receptor balance may be different in people with alcohol use disorder (AUD), using brain scans and blood testing. It may help researchers understand why some people respond differently to alcohol and related treatments.
This early-phase study looks at how alcohol affects impulsivity (tendency to act quickly) and people’s subjective experiences. You may be able to join if you drink regularly and meet the study safety rules.
This study uses a special brain scan to look at how stress and alcohol use affect the brain. It may help people with PTSD, alcohol use disorder, or healthy volunteers understand these conditions better.
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Hear when a new Familial Alcoholism Vulnerability trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.