Testing an alcohol brain imaging study based on opioid receptor balance
Part of Mental health clinical trials.
This early-phase study looks at how the brain’s opioid receptor balance may be different in people with alcohol use disorder (AUD), using brain scans and blood testing. It may help researchers understand why some people respond differently to alcohol and related treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a current diagnosis of alcohol use disorder (AUD) confirmed by the study team’s interview.
- If you have AUD: you must meet specific drinking amounts during a 30-day stretch within the last 90 days (different targets for men and women).
- If you join for AUD: you must be willing to try quitting alcohol and work toward staying abstinent.
- If you’re in the healthy group: you must not have ever been diagnosed with AUD or another major substance use disorder, and your recent drinking must be low (no “heavy drinking days”).
- You must be able to read/write English, sign consent, and agree to blood draws for a genetic test (OPRM1).
- You must be able to have MRI scans and have no metal/scan safety issues (for example, severe claustrophobia or metal in your body).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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