Testing centhaquine for severe breathing failure in the ICU
Treatments studied
Part of Lungs & breathing clinical trials.
This study tests a new drug called centhaquine for people with severe breathing problems (ARDS) in the ICU. The drug may help improve oxygen levels and recovery, and the study compares it to the usual care alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You need to be in the intensive care unit (ICU) with a diagnosis of moderate to severe ARDS, meaning your oxygen levels are very low despite extra oxygen.
- You must be on medication to support your blood pressure (vasopressors).
- The first dose of the study drug must be given within 48 hours of your ARDS diagnosis.
- You cannot participate if you are on a heart-lung machine (ECMO) or a special type of ventilation (high-frequency oscillatory ventilation), or if you are on dialysis or have severe liver failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study tests two types of breathing support—CPAP (a mask that pushes air into your lungs) and high-flow nasal oxygen (a special tube in your nose)—to see which works better for people with ARDS, a serious lung condition. It may help you breathe more easily without needing a breathing tube.
This trial tests a gentler way of using the breathing machine, and may add a machine that acts like an artificial lung, to give your lungs time to heal from ARDS. This could help you recover if your lungs are very strained.
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
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