Trazodone trial to improve sleep in early Alzheimer’s
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be diagnosed with mild cognitive impairment (MCI) with memory concerns that were measured on testing
- Have testing showing mild impairment (not dementia), such as a CDR around 0.5
- Have sleep complaints, with a sleep questionnaire score above a set cutoff
- Be able to complete memory testing and brain scans (MRI) and hear/see well enough for the tests
- Have a reliable “knowledgeable informant” (a spouse/family member/friend) who can answer questions about you
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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