MitraClip for advanced heart failure with leaky mitral valve
Part of Heart & circulation clinical trials.
This trial studies whether the MitraClip procedure can improve outcomes for people with advanced heart failure caused by significant leakage of the mitral valve. It focuses on people who still have severe symptoms and poor quality of life despite the best available heart medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- Your mitral valve leakage is significant, confirmed by an ultrasound test during screening.
- You have been on the best standard heart-failure medicines (optimal medical therapy) but still feel very unwell.
- Your heart failure is advanced, with severe symptoms and signs of weak heart function and/or high heart-stress blood tests.
- Your daily life and exercise ability are very limited, or you’ve needed an unplanned hospital visit in the last year for heart failure and may need IV “water pills” and/or heart support drugs.
- Your heart valve anatomy must be suitable for MitraClip, and certain dangerous heart/valve conditions (like blood clots or active infections) must be absent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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