CardioClip study: testing a new valve repair for leaky heart valve
Part of Heart & circulation clinical trials.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate to severe or severe mitral regurgitation (a leaky heart valve).
- Your heart's pumping strength (ejection fraction) is between 20% and 50%.
- You have heart failure symptoms like shortness of breath or fatigue during mild activity.
- You are willing to sign a consent form to join the study.
- Your heart valve's shape allows for a clip procedure (mitral valve edge-to-edge repair).
- You are not allergic to aspirin or clopidogrel.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether the MitraClip procedure can improve outcomes for people with advanced heart failure caused by significant leakage of the mitral valve. It focuses on people who still have severe symptoms and poor quality of life despite the best available heart medications.
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study looks at how well a clip (MitraClip G4) fixes a leaky heart valve in people with heart failure. If you are scheduled for this procedure, joining may help doctors learn more about the benefits of the clip.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
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