Skipping underarm surgery for some breast cancers after chemotherapy
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial studies whether it’s safe to skip removing underarm lymph nodes (axillary surgery) for people with certain breast cancers after they respond to “NACT,” a type of chemotherapy. It also uses planned breast-conserving surgery and whole-breast radiation to see if outcomes stay similar while reducing surgery-related side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can give written consent
- Your breast cancer has been confirmed by core biopsy as triple-negative or HER2-positive, and it started in one main area
- Before chemotherapy, your tumor and scans suggest no lymph-node spread and no distant spread (cT1c–T3, cN0, M0)
- If your lymph node looked suspicious on ultrasound, a biopsy of that node was negative
- After chemotherapy (NACT), imaging shows a response, and you plan breast-conserving surgery plus whole-breast radiation after surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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