Azacitidine to help prevent kidney injury after heart surgery
Treatments studied
Part of Kidney & urinary clinical trials.
This early-phase study tests whether azacitidine (a medication that changes how cells read genes) can lower the risk of acute kidney injury after cardiac surgery, especially in people already at risk along the chronic kidney disease (CKD) pathway. It aims to protect kidney function during the vulnerable period after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had cardiac surgery associated with acute kidney injury (AKI), and your AKI must be stage 2 or stage 3.
- You should NOT have chronic kidney disease (CKD) already.
- Your heart pumping strength should be okay: ejection fraction (EF) must not be below 45%.
- You must not have serious liver disease (cirrhosis classified as Child B or C).
- You should not have any active acute infection or active bleeding right now.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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