Botox injections for painful degenerative rotator cuff disease
Part of Bones, joints & muscles, Pain clinical trials.
This Phase 2 study tests whether botulinum toxin (Botox) injections can reduce pain from long-lasting degenerative rotator cuff problems. You may be eligible if you have shoulder pain for over a month and ultrasound evidence of specific tendon irritation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be over 40 years old
- Have shoulder pain for more than 1 month, with at least moderate pain and limited shoulder function
- Have had pain medicine in a stable way for at least 30 days before joining
- Have a recent shoulder ultrasound (within 30 days) showing supraspinatus tendon irritation, with or without a tear
- Be able to consent, come to all visits, and fill out the weekly pain/medication notebook
- If you can become pregnant: use reliable contraception starting 1 month before and continuing 1 month after, and have a negative urine pregnancy test
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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