TPX-115 injection for partial-thickness rotator cuff tear
Part of Bones, joints & muscles clinical trials.
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years old or older.
- You have a partial-thickness rotator cuff tear (less than half the tendon thickness) confirmed by MRI.
- You have had shoulder pain, weakness, and limited movement for more than 3 months, even after trying non-surgical treatments like physical therapy.
- Your shoulder pain is rated 4 or higher on a 0-to-10 scale.
- You do not have a full-thickness rotator cuff tear or other serious shoulder conditions.
- You have not taken painkillers in the last week, or had steroid injections or shoulder surgery recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether a single injection of stem cells from donated umbilical cord tissue can help people with a partial rotator cuff tear that hasn't healed with standard treatments like physical therapy or injections. If you have had shoulder pain for at least 3 months and a partial tear confirmed by MRI or ultrasound, you may be eligible.
This study tests whether injecting stem cells (special healing cells from umbilical cord tissue) into a partially torn rotator cuff can reduce pain and improve shoulder function. You may qualify if you have persistent shoulder pain from a partial tear that hasn't improved with physical therapy or injections.
This study tests an experimental treatment called TPX-115 for people with a partial-thickness rotator cuff tear. It aims to see if the treatment can reduce pain and improve function compared to standard care.
This trial tests if an injection of platelet-rich plasma (PRP) can help heal partial tears in the rotator cuff (shoulder tendons). It is for people who have had shoulder pain and limited movement for up to 3 months and have not had shoulder injections before.
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This study compares three types of injections—steroids, PRP (platelet-rich plasma), and PRP combined with hyaluronic acid—to see which works best for partial rotator cuff tears. If you have shoulder pain from a partial tear, this trial may help find the most effective treatment for you.
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