Compare two balloon types for calcium-heavy blocked heart arteries
Part of Heart & circulation clinical trials.
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and able to give consent.
- You have coronary artery disease with symptoms (like angina/chest pain) and/or test evidence of reduced blood flow to the heart.
- A heart angiogram shows a single “target” blockage in the left main, LAD, RCA, or LCX artery (or a branch), with specific narrowing and blood-flow findings.
- The blockage is strongly calcified, or you previously tried balloon treatment and it could not be expanded (or both).
- You can and will take a P2Y12 blood thinner (clopidogrel, prasugrel, or ticagrelor) for at least 6 months after the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a special balloon that helps prepare hardened blockages in the heart's arteries for stenting. It might improve outcomes for people with heavily calcified plaque.
This study tests a special balloon that can cut through hardened calcium in heart arteries before placing a stent. It may help people with severe artery calcification get a better stent placement.
This trial tests two ways to treat hardened, calcified blockages in heart arteries: shockwave therapy (lithotripsy) versus balloon angioplasty. It also looks at whether using a special imaging tool (OCT) during the procedure helps doctors choose the best treatment. This could improve outcomes for people with severe calcium buildup in their arteries.
This trial tests whether a drug-coated balloon (a tiny balloon that releases medicine) works as well as a drug-coated stent (a mesh tube) for treating hard calcium deposits in heart arteries. Patients first receive a special shockwave treatment to break up the calcium.
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
Hear when a new Coronary Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.