Clin2
NCT05363514Possibly a fitNot yet recruiting

Low dose naltrexone for POTS symptoms

Postural Orthostatic Tachycardia Syndrome

Treatments studied

Part of Brain & nervous system clinical trials.

This trial tests whether taking a very low dose of naltrexone (a medication that may help calm the immune system and reduce symptoms) can improve symptoms in people with POTS. If it works, it could offer a new, well-tolerated treatment option for this condition.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
80 people
Ages
18 years to 50 years
Study type
Interventional

Who can take part

  • You have a formal diagnosis of POTS from a doctor.
  • You can attend study visits in Calgary, Vancouver, or Hamilton, Canada.
  • You are not pregnant, not planning to become pregnant, and not breastfeeding during the study.
  • You are not currently taking low dose naltrexone or any opioid pain medications.
  • You do not have a history of alcohol, opioid, or other substance use disorder.
  • You are able to keep taking your other medications at the same doses during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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